Protein Structure(Biochemistry ) Questions and Answers

Question 1.  Beta pleated sheets are examples of protein's
  1.    primary structure
  2.    secondary structure
  3.    tertiary structure
  4.    quaternary structure
Explanation:-
Answer: Option B. -> secondary structure

Question 2.  BRACl, an inherited form of breast cancer, regulates cell division by
  1.    binding to a DNA sequence
  2.    complexing with cyclins
  3.    binding to the cell outer membrane
  4.    binding to the protein RAD 51 which repairs DNA damage
Explanation:-
Answer: Option D. -> binding to the protein RAD 51 which repairs DNA damage

Question 3.  Marfan's syndrome is thought to be a mutation affecting
  1.    hemoglobin synthesis
  2.    collagen synthesis
  3.    metabolism of homogentisic acid
  4.    insufficient thyroid production
Explanation:-
Answer: Option B. -> collagen synthesis

Question 4.  Individuals with PKU disease are mentally retarded unless
  1.    phenylalanine in the diet is restricted
  2.    tyrosine in the diet is restricted
  3.    homogentisic acid in the diet is restricted
  4.    none of the above
Explanation:-
Answer: Option A. -> phenylalanine in the diet is restricted

Question 5.  Cyclins are proteins that
  1.    regulate ability of cells to invade tissue
  2.    regulate passage from one stage of cell division to another
  3.    regulate apoptosis of damaged cells
  4.    none of the above
Explanation:-
Answer: Option B. -> regulate passage from one stage of cell division to another

Question 6.  Metastasis involves
  1.    ability of cells to dissolve cellular matrix
  2.    metalloprotein levels
  3.    decreased levels of proteins that regulate metalloproteins
  4.    all of the above
Explanation:-
Answer: Option D. -> all of the above

Question 7.  Signal sequences are part of a protein that
  1.    signal folding of the protein
  2.    signal the protein synthesis on the ribosomes is ended
  3.    transport proteins to other sites within the cell
  4.    refold proteins in prion-associated diseases
Explanation:-
Answer: Option C. -> transport proteins to other sites within the cell

Question 8.  Over 50% of common cancers are associated with damage to a protein, p53. This protein
  1.    is a cyclin
  2.    is a tumor supressor
  3.    is an oncogene
  4.    regulates apoptosis
Explanation:-
Answer: Option B. -> is a tumor supressor

Question 9.  Protein folding is
  1.    automatic, mediated by the protein itself
  2.    mediated by other proteins called chaperones
  3.    mediated by the ribosomes
  4.    none of the above
Explanation:-
Answer: Option B. -> mediated by other proteins called chaperones

Question 10. . Sickle cell disease is due to
  1.    a mutation in the beta chain of Hb
  2.    a mutation in the alpha chain of Hb
  3.    infection with a parasite
  4.    none of the above
Explanation:-
Answer: Option A. -> a mutation in the beta chain of Hb