Fatty Acid Catabolism(General Knowledge > General Science ) Questions and Answers

Question 1. The long-chain fatty acids get transported through the inner mitochondrial membrane
  1.    freely
  2.    as acyl-CoA derivative
  3.    as carnitine derivative
  4.    require sodium-dependent carrier
Explanation:-
Answer: Option C. -> as carnitine derivative
Question 2. Where do the long-chain fatty acids get first activated?
  1.    Microsomes
  2.    Mitochondria
  3.    Cytosol
  4.    Nucleus
Explanation:-
Answer: Option C. -> Cytosol
Question 3. In what compartment does the de novo fatty acid synthesis occur?
  1.    Mitochondria
  2.    Peroxisome
  3.    Cytosol
  4.    Endoplasmic reticulum
Explanation:-
Answer: Option C. -> Cytosol
Question 4. Which of the following undergoes β-oxidation?
  1.    Polyunsaturated fatty acids
  2.    Monounsaturated fatty acids
  3.    Saturated fatty acids
  4.    All of the above
Explanation:-
Answer: Option D. -> All of the above
Question 5. The free fatty acids are transported by blood associated with
  1.    a fatty acid-binding protein
  2.    β -lipoprotein
  3.    albumin
  4.    none of the above
Explanation:-
Answer: Option C. -> albumin
Question 6. What is the allosteric regulator of acetyl CoA carboxylase?
  1.    Fatty acid
  2.    ATP
  3.    Citrate
  4.    Acetyl CoA
Explanation:-
Answer: Option C. -> Citrate
Question 7. The irreversibility of the thiokinase reactions (formation of acyl-CoA)
  1.    is due to the subsequent hydrolysis of the PPi product.
  2.    makes this activation (or "priming") reaction the committed step on the pathway.
  3.    The first and second choices are both correct.
  4.    applies only to even-chain fatty acids.
Explanation:-
Answer: Option C. -> The first and second choices are both correct.
Question 8. Lipoprotein lipase acts in:
  1.    hydrolysis of triacylglycerol's of plasma lipoproteins to supply fatty acids to various tissues.
  2.    intestinal uptake of dietary fat.
  3.    intracellular lipid breakdown of lipoproteins.
  4.    none of the above.
Explanation:-
Answer: Option A. -> hydrolysis of triacylglycerol's of plasma lipoproteins to supply fatty acids to various tissues.
Question 9. Which of these is able to cross the inner mitochondrial membrane?
  1.    Acetyl–CoA
  2.    Fatty acyl–carnitine
  3.    Fatty acyl–CoA
  4.    Malonyl–CoA
Explanation:-
Answer: Option B. -> Fatty acyl–carnitine
Question 10. What is the precursor for fatty acid synthesis?
  1.    Propionyl CoA
  2.    Acetyl CoA
  3.    Succinyl CoA
  4.    Acetoacetyl CoA
Explanation:-
Answer: Option B. -> Acetyl CoA
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