Synthesis Of Therapeutic Agents(Biotechnology ) Questions and Answers

Question 1. The gene coding for VP1 is cloned in
  1.    pUC 19
  2.    pMB 9
  3.    pBR 322
  4.    pUC 18
Explanation:-
Answer: Option C. -> pBR 322
Question 2. Chemically synthesized DNA sequences for the two chains are separately inserted into the plasmid pBR 322 by the side of
  1.    glucokinase
  2.    acid phosphatase
  3.    galactokinase
  4.    β-Galactosidase
Explanation:-
Answer: Option D. -> β-Galactosidase
Question 3. How many nucleotides are there in Ss RNA molecule of picorna virus causing FMD?
  1.    5000
  2.    8000
  3.    1000
  4.    10000
Explanation:-
Answer: Option B. -> 8000
Question 4. Recombinant vaccine for Hepatitis B virus has been synthesized against which of the following antigen?
  1.    e antigen (HBeAg)
  2.    Viral surface antigen (HBsAg)
  3.    Viral core antigen (HBcAg)
  4.    All of these
Explanation:-
Answer: Option B. -> Viral surface antigen (HBsAg)
Question 5. Human insulin formed by recombinant DNA technology is known as
  1.    R insulin
  2.    huinsulin
  3.    humulin
  4.    H insulin
Explanation:-
Answer: Option C. -> humulin
Question 6. Human growth hormone (hGH) is secreted by
  1.    pancreas
  2.    pitutary gland
  3.    hypothalamus
  4.    none of these
Explanation:-
Answer: Option B. -> pitutary gland
Question 7. The first therapeutic product formed by means of recombinant DNA technology is
  1.    vaccine for foot and mouth disease
  2.    insulin
  3.    human growth hormone
  4.    hepatitis B vaccine
Explanation:-
Answer: Option B. -> insulin
Question 8. Recombinant vaccine for HBV was produced by cloning viral genes in
  1.    cosmids
  2.    phagemids
  3.    plasmids
  4.    autonomously replicating plasmid of yeast
Explanation:-
Answer: Option D. -> autonomously replicating plasmid of yeast
Question 9. The promoter used for cloning HBV surface antigen is
  1.    polyhedrin
  2.    alcohol dehydrogenase 1
  3.    β-galactosidase
  4.    galactokinase
Explanation:-
Answer: Option B. -> alcohol dehydrogenase 1
Question 10. Which one of the following capsid protein of picorna virus is immunogenic in nature?
  1.    VP2
  2.    VP3
  3.    VP4
  4.    VP1
Explanation:-
Answer: Option D. -> VP1
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