Retroviridae(Microbiology ) Questions and Answers

Question 1. HIV can infect
  1.    M (membranous) cells
  2.    All of these
  3.    Microglial cells
  4.    CD4 + T lymphocytes
Explanation:-
Answer: Option B. -> All of these
Question 2. Parasitic infection/s frequently observed in HIV disease is / are.
  1.    all of these
  2.    isosporiasis
  3.    toxoplasmosis
  4.    cryptosporidiosis
Explanation:-
Answer: Option A. -> all of these
Question 3. The commonest bacterial infection in HIV disease is/are
  1.    all of these
  2.    mycobacterial infection
  3.    salmonella infection
  4.    bartonella infection
Explanation:-
Answer: Option B. -> mycobacterial infection
Question 4. What is the average incubation period for development of AIDS?
  1.    Ten years
  2.    Twenty years
  3.    One year
  4.    Five years
Explanation:-
Answer: Option A. -> Ten years
Question 5. Viral infections frequently observed in HIV disease is /are
  1.    cytomegalo virus
  2.    herpes simplex
  3.    varicella- zoster
  4.    all of these
Explanation:-
Answer: Option D. -> all of these
Question 6. The commonest opportunistic infection in AIDS patient in India is
  1.    cryptococcosis
  2.    cryptosporidiosis
  3.    toxoplasmosis
  4.    tuberculosis
Explanation:-
Answer: Option D. -> tuberculosis
Question 7. HIV belongs to the family retroviridae and sub-family
  1.    Lentivirinae
  2.    Oncovirinae
  3.    Spumavirinae
  4.    None of these
Explanation:-
Answer: Option A. -> Lentivirinae
Question 8. HIV or Human Immunodeficiency Virus is considered unique because each virus contains:
  1.    a genome made up of both DNA and RNA components
  2.    sticky proteins that allow it to bind tightly to host cells
  3.    a viral enzyme known as reverse transcriptase
  4.    more than 100 copies of the viral genome
Explanation:-
Answer: Option C. -> a viral enzyme known as reverse transcriptase
Question 9. The confirmatory test(s) for HIV infection is/are
  1.    detection of viral nucleic acid
  2.    All of these
  3.    detection of p24 antigen
  4.    virus isolation
Explanation:-
Answer: Option B. -> All of these
Question 10. Which of the following is transmembrane pedicle antigen of HIV-I?
  1.    gp 140
  2.    gp 41
  3.    gp l20
  4.    gp 36
Explanation:-
Answer: Option B. -> gp 41
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