Disorders In Biotechnology(Biotechnology ) Questions and Answers

Question 1. If the RBC of human were kept in 0.9% NaCl solution, what sort of change will occur to RBC?
  1.    No change to RBC
  2.    Cell will Burst
  3.    RBC will destroy
  4.    Cell will shrink
Explanation:-
Answer: Option A. -> No change to RBC
Question 2. Which of the modification in hemoglobin is the cause of sickle cell anemia?
  1.    A mutation in the beta chain
  2.    Replacement of the B chain by D chain
  3.    A deletion in the beta chain
  4.    None of these
Explanation:-
Answer: Option A. -> A mutation in the beta chain
Question 3. The disorder in which of the following may cause "Ehlers-Danlos Syndrome"?
  1.    Fibrin protein
  2.    Globulin protein
  3.    Collagen protein
  4.    Dlashin protein
Explanation:-
Answer: Option C. -> Collagen protein
Question 4. Which of the protein is involved in Alzheimer's disease?
  1.    Fibrin
  2.    A4
  3.    Alzhemin
  4.    Amylin
Explanation:-
Answer: Option B. -> A4
Question 5. Klinefelter syndrome is a manifestation of which chromosome aneuploidy?
  1.    XXX
  2.    None of these
  3.    XYY
  4.    XXY
Explanation:-
Answer: Option D. -> XXY
Question 6. During sickle cell anemia which of the following takes place?
  1.    Valine change to glutamine
  2.    Glutamic acid change to aspartic acid
  3.    Glutamine change to valine
  4.    Aspartic acid change to glutamic acid
Explanation:-
Answer: Option C. -> Glutamine change to valine
Question 7. What is the defective enzyme in the glycogen storage Von Gierke's disease?
  1.    Glucose-6-phosphatase
  2.    Phosphofructokinase
  3.    None of these
  4.    Phosphorylase
Explanation:-
Answer: Option A. -> Glucose-6-phosphatase
Question 8. A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause
  1.    Ehlers-Danlos syndrome
  2.    Kleinefelter's syndrome
  3.    Gaucher's disease
  4.    Lesch- Nyhan syndrome
Explanation:-
Answer: Option D. -> Lesch- Nyhan syndrome
Question 9. Methotrexate is toxic to human cells because it inhibits
  1.    reduction of H2 folate to H4 folate
  2.    None of these
  3.    formation of CTP from UTP
  4.    synthesis of PRPP
Explanation:-
Answer: Option A. -> reduction of H2 folate to H4 folate
Question 10. Which of the following sets belongs to a distinct class or category?
  1.    Ribose, sucrose, glucose, fructose
  2.    Oils, sterols, waxes, fats
  3.    Sterols, waxes, fatty acids, amino acids.
  4.    Nucleotide, nucleoside, nucleus, DNA
Explanation:-
Answer: Option C. -> Sterols, waxes, fatty acids, amino acids.
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