Bioavailability And Bioequivalence(Drug And Pharmaceutical Biotechnology ) Questions and Answers

Question 1. Which of the following is used in solid solutions method of enhancing bioavailability?
  1.    Highly water-soluble compound
  2.    Organic solvent
  3.    Inorganic clays like bentonite
  4.    Creating metastable polymorphs
Explanation:-
Answer: Option A. -> Highly water-soluble compound
Answer: (a).Highly water-soluble compound
Question 2. Which of the following is used in the solvent deposition method of enhancing bioavailability?
  1.    Freeze drying
  2.    Organic solvent
  3.    Inorganic clays like bentonite
  4.    Creating metastable polymorphs
Explanation:-
Answer: Option B. -> Organic solvent
Answer: (b).Organic solvent
Question 3. In the given picture, the marking “a” represents the drug concentration of which compartment?In The Given Picture, The Marking “a” Represents The Dru...
  1.    The central compartment in a two compartment model
  2.    A peripheral compartment in a two compartment model
  3.    The central compartment in a one compartment model
  4.    Drug concentration of the plasma
Explanation:-
Answer: Option A. -> The central compartment in a two compartment model
Answer: (a).The central compartment in a two compartment model
Question 4. At which of the four marked points of the plasma drug concentration versus time graph, absorption rate = elimination rate?At Which Of The Four Marked Points Of The Plasma Drug Concen...
  1.    a
  2.    b
  3.    c
  4.    d
Explanation:-
Answer: Option A. -> a
Answer: (a).a
Question 5. Which of the following is used in molecular encapsulation of drugs for enhancing bioavailability?
  1.    Highly water-soluble compound
  2.    Cyclodextrin
  3.    Inorganic clays like bentonite
  4.    Creating metastable polymorphs
Explanation:-
Answer: Option B. -> Cyclodextrin
Answer: (b).Cyclodextrin
Question 6. In the below picture which form of solid solution of griseofulvin with succinic acid is shown?In The Below Picture Which Form Of Solid Solution Of Griseof...
  1.    Solid solution
  2.    Eutectic mixture
  3.    Micronized drug
  4.    Coarse drug
Explanation:-
Answer: Option D. -> Coarse drug
Answer: (d).Coarse drug
Question 7. What is the equation of bioavailable fraction?
  1.    1/Bioavailable dose
  2.    1/Administered dose
  3.    Bioavailable dose/Administered dose
  4.    Administered dose/Bioavailable dose
Explanation:-
Answer: Option C. -> Bioavailable dose/Administered dose
Answer: (c).Bioavailable dose/Administered dose
Question 8. Single-dose bioavailability studies are simple and common.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 9. Which of the following is the pharmacodynamics method of studying bioavailability?
  1.    Acute pharmacologic response
  2.    Plasma-level time studies
  3.    Urinary excretion studies
  4.    Stool excretion studies
Explanation:-
Answer: Option A. -> Acute pharmacologic response
Answer: (a).Acute pharmacologic response
Question 10. Which of the following is not an objective of bioavailability studies?
  1.    Primary stages of development of suitable dosage form for new drug
  2.    Determination of the influence of excipients, patient-related factors, etc
  3.    Development of new formulations of the existing drugs
  4.    Control the quantity of the drug to be administered
Explanation:-
Answer: Option D. -> Control the quantity of the drug to be administered
Answer: (d).Control the quantity of the drug to be administered
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