Protein Biomolecular Interactions(Bioinformatics ) Questions and Answers

Question 1. The investigation (Aloy and Russel) of domain combinations in multidomain proteins by Bashton and Chothia focuses on two-domain proteins belonging to the Rossmann domain family.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 2. The linkers between the catalytic domain and the Rossmann domain were conserved in each family.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 3. Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______
  1.    single gene in at least one genome
  2.    multiple genes in at least one genome
  3.    multiple genes in various genomes
  4.    single gene in various genomes
Explanation:-
Answer: Option A. -> single gene in at least one genome
Answer: (a).single gene in at least one genome
Question 4. Across the different types of catalytic families, the position of the two domains with respect to one another varied, but only within a range of about ______
  1.    20°
  2.    10°
  3.    90°
  4.    80°
Explanation:-
Answer: Option C. -> 90°
Answer: (c).90°
Question 5. Experimentation is most desirable over computational methods by every means.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 6. In the phylogenetic profile method for predicting protein interaction, presence or absence of orthologous genes is scored across a variety of genomes.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 7. The most detailed experimental information about protein-protein interactions comes from three-dimensional structures.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 8. Structural analyses on small sets of proteins have shown that the domains from a pair of families bind to each other with the same geometry in multi-domain proteins and in transient interactions.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
Question 9. In Grid representation, the lowest score represents the best surface complementarity for a given translational scan.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 10. In Property-based measures, displaying physical properties on the molecular surface of molecules can help to guide molecular docking.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option A. -> True
Answer: (a).True
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