Absorption Of Drugs(Drug And Pharmaceutical Biotechnology ) Questions and Answers

Question 1. Which option will be the best example of the physicochemical properties of drugs?
  1.    Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability, pH, Pressure of disintegration
  2.    Pressure of disintegration, polymorphism, salt form, pseudopolymorphism, complexation, wettability, pH
  3.    Solubility, particle size, polymorphism, salt form
  4.    Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability
Explanation:-
Answer: Option D. -> Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability
Answer: (d).Solubility, particle size, polymorphism, salt form, pseudopolymorphism, complexation, wettability
Question 2. For oral formulation, what should be the minimum aqueous solubility to avoid bioavailability problems?
  1.    0.9%
  2.    1%
  3.    2%
  4.    0.11%
Explanation:-
Answer: Option B. -> 1%
Answer: (b).1%
Question 3. Particle size and surface area of a drug are directly related to each other.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 4. Absolute surface area is proportional to the dissolution rate of a drug.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 5. The total solid surface area of any particle is known as ___________
  1.    Absolute surface area
  2.    Effective surface area
  3.    Total surface area
  4.    Surface area
Explanation:-
Answer: Option A. -> Absolute surface area
Answer: (a).Absolute surface area
Question 6. Capsules with bigger particles and intense packing have poor drug release and dissolution rate due to an increase in the pore size.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 7. Which one of them is not a common form of excipients of drug manufacturing?
  1.    Diluents
  2.    Binders
  3.    Sweeteners
  4.    Essential oils
Explanation:-
Answer: Option D. -> Essential oils
Answer: (d).Essential oils
Question 8. Vehicles are the solvent system for the liquefied drug. Which one of them is not an example of a kind of vehicle?
  1.    Aqueous vehicle
  2.    Non-aqueous water-miscible vehicles
  3.    Non-aqueous water immiscible vehicles
  4.    A salt solution of the drug
Explanation:-
Answer: Option D. -> A salt solution of the drug
Answer: (d).A salt solution of the drug
Question 9. What is the function of a granulating agent in drug formulation?
  1.    Promote cohesive compacts
  2.    Added if the required dosage is inadequate so that necessary bulk can be produced
  3.    Tablets can disintegrate easily
  4.    Used as solubilizer
Explanation:-
Answer: Option A. -> Promote cohesive compacts
Answer: (a).Promote cohesive compacts
Question 10. Which one of the following will be an example of organic diluents?
  1.    Starch
  2.    Dicalcium phosphate
  3.    Tetracycline
  4.    Tween 80
Explanation:-
Answer: Option A. -> Starch
Answer: (a).Starch
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