Antibiotics And Chemotherapeutic Agents(Microbiology ) Questions and Answers

Question 1. Which of the following is not a characteristic of a chemotherapeutic agent?
  1.    low toxicity for host cells
  2.    high toxicity for the parasites
  3.    less penetrating power
  4.    does not affect the host’s natural defense mechanism
Explanation:-
Answer: Option C. -> less penetrating power
Answer: (c).less penetrating power
Question 2. Sulfonamides and arsphenamine are similar in their specificity for a special group of organism.
  1.    True
  2.    False
  3.    May be
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 3. Which was the first disease for which a chemotherapeutic agent was used?
  1.    Syphilis
  2.    Malaria
  3.    Small pox
  4.    AIDS
Explanation:-
Answer: Option A. -> Syphilis
Answer: (a).Syphilis
Question 4. Phenol is considered as a chemotherapeutic agent.
  1.    True
  2.    False
  3.    May be
  4.    Can't say
Explanation:-
Answer: Option B. -> False
Answer: (b).False
Question 5. Sulfanilamide was synthesized by which of the following research scientists?
  1.    Eisenberg
  2.    Gelmo
  3.    Ehrlich
  4.    Domagk
Explanation:-
Answer: Option B. -> Gelmo
Answer: (b).Gelmo
Question 6. The scientist who first discovered the substance penicillin was
  1.    Joseph Lister
  2.    Alexander Fleming
  3.    Paul Ehrlich
  4.    none of these
Explanation:-
Answer: Option B. -> Alexander Fleming
Answer: (b).Alexander Fleming
Question 7. With which of the following aminoglycosides interfere?
  1.    Protein synthesis
  2.    DNA function
  3.    Cell wall synthesis
  4.    Cell membrane function
Explanation:-
Answer: Option A. -> Protein synthesis
Answer: (a).Protein synthesis
Question 8. Which of the following protein synthesis mechanisms may be affected by particular drugs?
  1.    Peptide bond formation
  2.    mRNA translocation
  3.    Aminoacyl-tRNA binding
  4.    All of these
Explanation:-
Answer: Option D. -> All of these
Answer: (d).All of these
Question 9. The larger the __________ , the better the chemotherapeutic agent.
  1.    therapeutic index
  2.    therapeutic dose
  3.    selective toxicity
  4.    spectrum
Explanation:-
Answer: Option A. -> therapeutic index
Answer: (a).therapeutic index
Question 10. Chelate forming peptide antibiotic are/is
  1.    bleomycins
  2.    sideromycins
  3.    both (a) and (b)
  4.    vancomycin
Explanation:-
Answer: Option C. -> both (a) and (b)
Answer: (c).both (a) and (b)
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